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| G6PD Quantitative Test |
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| Measures G6PD enzyme levels to diagnose deficiency, causing anemia or jaundice | ||
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Synonym | G-6-PD Quant Test |
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Test Code | CHEM250047 |
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Test Type | Hematology |
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Pre-Test Condition | No special |
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Report Availability | 1–2 D(s) |
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# Test(s) | 1 |
| Test details | Sample Report |
|---|---|
| G6PD Quantitative Test |
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| Synonym | G-6-PD Quant Test | |
| Test Code | CHEM250047 | |
 | Test Category | ||
| Pre-Test Condition | No special | |
 | Medical History | Share & see Updates | |
| Report Availability | 1–2 D(s) | |
 | Specimen/Sample | Refer Updates | |
 | Stability @21-26 deg. C | 24 H(s) | |
 | Stability @ 2-8 deg. C | 48 H(s) | |
 | Stability @ Frozen | Not frozen | |
| # Test(s) | 1 | |
 | Processing Method | Spectrophotometry | |
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Overview: G6PD Quantitative Test
Introduction: The G6PD Quantitative Test measures G6PD enzyme levels to diagnose deficiency, causing anemia or jaundice. Following 2023 ASH guidelines, it uses spectrophotometry for high sensitivity, aiding in hematological screening. This test is critical for guiding diagnosis, management, and improving outcomes in hematology for patients with suspected G6PD deficiency. Other Names: G6PD Quantitative Assay, Glucose-6-Phosphate Dehydrogenase Level Test. FDA Status: Laboratory-developed test (LDT), meeting hematology standards for diagnostic accuracy. Historical Milestone: G6PD quantitative testing began in the 1970s with hematology research. Spectrophotometry improved in the 1990s, enhancing accuracy for enzyme level measurement. Purpose: Diagnoses G6PD deficiency, guides trigger avoidance, and quantifies enzyme levels in patients with anemia or jaundice. Test Parameters: 1. Glucose-6-Phosphate Dehydrogenase Pretest Condition: No fasting required. Collect whole blood at any time. Report symptoms like anemia or jaundice, and list triggers or medications. Specimen: 2-5 mL whole blood (EDTA). Transport in a biohazard bag within 24 hours. Sample Stability at Room Temperature: 24 hours Sample Stability at Refrigeration: 48 hours Sample Stability at Frozen: Not frozen Medical History: Document anemia, jaundice, or history of G6PD deficiency. Include triggers (e.g., fava beans, drugs) and current medications. Consent: Written consent required, detailing the tests purpose, diagnostic implications, and potential need for trigger avoidance. Procedural Considerations: Uses spectrophotometry to quantify G6PD enzyme levels. Results are available in 1-2 days, enabling rapid clinical decisions. Factors Affecting Result Accuracy: Hemolysis or improper storage can affect results. Recent transfusions may mask deficiency. Clinical Significance: Low G6PD levels confirm deficiency, prompting trigger avoidance. Normal levels may require genetic testing. Specialist Consultation: Consult a hematologist for result interpretation. Additional Supporting Tests: G6PD mutation test, CBC, or reticulocyte count to confirm deficiency. Test Limitations: False negatives may occur post-transfusion. Results require clinical correlation. References: ASH G6PD Guidelines, 2023; Blood, Cappellini MD, 2022. |