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**17 OH Corticosteroids 24Hr Urine****FDA Status**: Standard laboratory procedure under CLIA; no specific FDA approval required.**Other Names**: 17-Hydroxycorticosteroids Urine Test, Adrenal Function Test.**Historical Breakthrough**: Developed in the 1950s to assess adrenal function, advancing endocrinology.**Key Purpose and Impact**: Measures 17-hydroxycorticosteroids in 24-hour urine to diagnose Cushing’s syndrome or adrenal insufficiency.**Preparation and Patient History**: 24-hour urine; report weight gain, fatigue, or adrenal history.**Consent Requirement**: Standard consent for non-invasive sample collection.**Clinical Value**: Sensitivity ~90%; specificity ~95%; detects abnormalities in ~80% of cases; guides diagnosis.**References Cited**: Testing.com Endocrine Tests 2023; Labcorp 17-OHCS Test 2025; UpToDate Adrenal Disorders 2025 |