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**Creatinine and Estimated Glomerular Filtration Rate****FDA Status**: Standard laboratory procedure under CLIA; no specific FDA approval required.**Other Names**: Creatinine and eGFR Test, Renal Function Test.**Historical Breakthrough**: Developed in the 1970s to assess kidney function, advancing nephrology.**Key Purpose and Impact**: Measures serum creatinine and calculates eGFR to evaluate kidney filtration capacity.**Preparation and Patient History**: Blood; report edema, hypertension, or kidney history.**Consent Requirement**: Standard consent for diagnostic testing.**Clinical Value**: Sensitivity ~90%; specificity ~95%; detects kidney dysfunction in ~80% of cases; guides therapy.**References Cited**: Testing.com Kidney Tests 2023; Labcorp Creatinine/eGFR Test 2025; UpToDate Kidney Function 2025 |